2010 International symposium on dupuytren disease
The
2010
International
Symposium
on
Dupuytren's Disease
was a comprehensive review of Dupuytren's Disease,
combining
invited reviews with presentations of new
material by world experts. The goal of this symposium
was to
promote a global collaborative effort to
develop better treatment options for Dupuytren's
disease and related
conditions, and this is now underway.
PDF abstracts of individual presentations may be viewed by clicking on the presentation title links.
The full program with abstracts and biographies is here.
Videos of individual presentations may be viewed by clicking on
to watch on YouTube or 
to download as an iPod compatible mp4
video file.SYMPOSIUM
PROGRAM
Sat May 22
7:00 - 8:00 Breakfast
8:00 - 10:00 Session 1: Introductory Comments and Concepts
10:15 - 12:15 Session 2: The Myofibroblast
1:00 - 3:00 Session 3: Demographics and Genetics
3:15 - 5:15 Session 4: Collagen and Cell Biology
7:00 - 9:00 Dinner Reception and Presentation
Sun May 23
7:00 - 8:00 Breakfast
8:00 - 10:00 Session 5: Surgical Treatments
10:15 – 12:15 Session 6: Needle Release and Manual Therapy
1:00 – 3:00 Session 7: Biologic Intervention: Dupuytren's and Related Conditions
3:15 - 5:15 Session 8: The Future
7:00 - 8:00 Breakfast
8:00 - 10:00 Session 1: Introductory Comments and Concepts
- Charles Eaton MD: Introductory Remarks.
- Wolfgang Wach PhD: The Development of the
Dupuytren Society.
- Lee Osterman MD: Cline’s contracture:
Dupuytren was a thief. A history of surgery for
Dupuytren’s contracture.
- Ghazi Rayan MD: Dupuytren's disease:
anatomy, pathology, presentation.
- Ardeshir Bayat MD PhD: Genetics of
Dupuytren's.
- Albrecht Meinel MD: The palmar
fibromatosis or the loss of flexibility of the
palmar finger tissue. A new insight into the
disease process of Dupuytren’s contracture based
on clinical and anatomical findings.
- Hanno Millesi MD: Changes of the
visco-elastic properties of the palmar fascia as
pathogenetic basis of Dupuytren’s Disease.
10:15 - 12:15 Session 2: The Myofibroblast
- Paul Werker MD PhD: Management of soft
tissue contractures: a surgical perspective
- Paul Zidel MD MS: Dupuytren's versus burn
scar contracture.
- Boris Hinz PhD: Fundamental aspects of
myofibroblast contraction.
- Sem Phan PhD MD : Mechanisms of
myofibroblast differentiation..
- Véronique Moulin PhD : Tissue engineering and
the myofibroblasts.
- Giulio Gabbiani PhD MD: The N-terminal
peptide of a-smooth muscle actin Ac-EEED inhibits
myofibroblast contraction: therapeutic
implications.
- Heinrich Seegenschmiedt MD: Review Of
Radiotherapy For Morbus Dupuytren &
Ledderhose.
1:00 - 3:00 Session 3: Demographics and Genetics
- Guido Dolmans MD: A clinical genetic
study of familial Dupuytren’s Disease in the
Netherlands.
- Vilhjalmur Finsen PhD: The epidemiology of
Dupuytren’s disease in Bosnia.
- Hans Hennies PhD: Characterization of
the epidemiology and genetic basis for Dupuytren
Contracture.
- Guido Dolmans MD: A first genome-wide
association study in Dupuytren’s disease.
- Sandeep Kathju MD PhD: Establishing an animal
model of Dupuytren’s contracture by
profiling genes associated with fibrosis.
- Ivana Ratkaj PhD: Microarray expression
analysis of Dupuytren´s contracture.
- Guido Dolmans MD: Linkage analysis in
six Dutch families with Dupuytren’s disease.
3:15 - 5:15 Session 4: Collagen and Cell Biology
- Susan Hart VMD PhD: A primer of collagen
biology: synthesis, degradation, subtypes
and role in Dupuytren’s contracture.
- Janine Morris PhD: Collagen degradation
and the expression of proteases involved in
collagen metabolism in the contraction of collagen
gels by Dupuytren’s disease-derived fibroblasts.
- Martin Robson MD: Using laboratory
models to develop molecular mechanistic treatments
for Dupuytren’s disease.
- David O'Gorman PhD: Primary Dupuytren's
Disease cell interactions with the extra-cellular
environment: a link to disease progression?
- Christina Raykha MSc: Insulin-like Growth
Factor Binding Protein (IGFBP)-6: A mediator of
myofibroblast differentiation in Dupuytren’s
Disease?
7:00 - 9:00 Dinner Reception and Presentation
- Paul Wylock MD: A Working Day of Guillame Dupuytren
Sun May 23
7:00 - 8:00 Breakfast
8:00 - 10:00 Session 5: Surgical Treatments
- Lynn Ketchum MD : Dermofasciectomies
and full-thickness skin grafts in the treatment of
Dupuytren's contracture: a thirty-six year study.
- Robert Choa MD: Palmar Cutaneous
Branches of the Proper Digital Nerves Encountered
in Dupuytrens Surgery: a Cadaveric Study.
- Andrey Zhigalo MD: The features of
surgical tactic in treatment of patients with
severe stages Dupuytren contracture.
- Ilse Degreef PhD MD: Surgical outcome of
Dupuytren’s disease. No higher self-reported
recurrence after segmental fasciectomy.
- Michael Papaloïzos MD: Minimizing
cutaneous necrosis and delayed healing after
surgical treatment for Dupuytren’s contracture :
the mini-chevrons incision.
- Bernhard Lukas MD: Treatment of severe
Dupuytren contracture by homodigital flaps.
- Massimiliano Tripoli MD: The “Jacobsen
flap” for the treatment of stage III-IV
Dupuytren's disease at the little finger: our
review of 123 cases.
- Paul Smith MD: A Logical Approach to
the PIP Joint in Dupuytren's.
10:15 – 12:15 Session 6: Needle Release and Manual Therapy
- Holger Erne MD: Percutaneous needle
fasciotomy a serious alternative?
- Annet Van Rijssen MD: 5-year results of
first-ever randomised clinical trial on treatment
in Dupuytren's disease: percutaneous needle
fasciotomy versus limited fasciectomy.
- Roger Khouri MD: Extensive Percutaneous
Aponeurotomy and Lipografting: A new treatment
alternative for Dupuytren's disease.
- Bing Siang Gan PhD MD: Needle aponeurotomy for
Dupuytren's contracture, the HULC experience.
- John Agee MD: Growing the PIP straight
with the Digit Widget.
- Terri Skirven OTR/L CHT: Hand therapy for
Dupuytren's: Concepts, practical tips and
problems.
- Albrecht Meinel MD: The role of static
night splinting after contracture release for
Dupuytren’s disease. A preliminary recommendation
based on clinical cases.
- Deborah Larson BScOT, MSc: Splinting after
contracture release for Dupuytren’s disease
(SCoRD) – a pragmatic, multi-centre, randomized
controlled trial.
1:00 – 3:00 Session 7: Biologic Intervention: Dupuytren's and Related Conditions
- Marie Badalamente PhD: Injectable
collagenase clostridium histolyticum for
Dupuytren's contracture: results of the cord 1
study.
- Anne Ouellette MD MBA: Outcomes of
Apligraf use in Dupuytren's surgery using the
McCash incision improves long term outcome.
- Ilse Degreef PhD MD: Cellular implant
improves surgical outcome in Dupuytren’s disease.
- Heinrich Seegenschmiedt MD: Radiotherapy
For Primary Or Recurrent Morbus Ledderhose: 12
Year Long-Term Outcome Of A Prospective Phase 2
Trial.
- Wayne Hellstrom MD: Medical Management
of Peyronie’s Disease.
- Terry Spilken DPM: Cryotherapy for
Plantar Fibromas.
- Chrishan Samuel PhD: Relaxin: an emerging
therapy for fibroproliferative disorders.
- Davor Jurisic PhD MD: Screening of
potential prodrugs on cells derived from
Dupuytren's disease patients.
- Ilse Degreef PhD MD: Highly-dosed
neo-adjuvant tamoxifen improves surgical outcome
in segmental fasciectomy in high risk patients
with Dupuytren’s disease.
3:15 - 5:15 Session 8: The Future
- Panel Discussions: Global collaboration for Dupuytren’s and related conditions.
- Charles Eaton MD: Closing remarks.